Cefpiramide acid

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

头孢匹胺是第三代头孢菌素类抗生素。

Cefpiramide is a third-generation cephalosporin antibiotic.

Cefpiramide (0-2048 μg/mL; 16-18 hours) shows good activity to against most non-fermentative Gram-negative bacilli and Enterococci (32 μg/mL with 97% inhibition).Cefpiramide (0-2048 μg/mL; 16-18 hours) exhibits high effective to against Pseudomonas aeruginosa with MIC[50] and MIC[90] values of 4 μg/mL and 16 μg/mL separately. Cell Viability Assay Cell Line:761 bacterial isolates (35 different species of common bacterial pathogens) Concentration:0-2048 μg/mL Incubation Time:16-18 hours Result:Showed broad-spectrum antibacterial activity.

Cefpiramide (25 mg/kg; i.v.; once) shows anti-Streptococcus pneumoniae activity in experimental pneumococcal meningitis.Cefpiramide (25 mg/kg; i.v.; once) reduces bacteria in CSF more than 10 CFU/ml. Animal Model:New Zealand white male rabbits(2-3 kg).Dosage:25 mg/kg Administration:Intravenous injection; once.Result:Anti-Streptococcus pneumoniae.

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GPCR/G Protein

Antibacterial

PBPs

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70797-11-4

612.64

C25H24N8O7S2

>98% (HPLC)

Water: insoluble; DMSO: insoluble

CC1=CC(=O)C(=CN1)C(=O)N[C@H](C2=CC=C(C=C2)O)C(=O)N[C@H]3[C@@H]4N(C3=O)C(=C(CS4)CSC5=NN=NN5C)C(=O)O

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(-20℃)

With Ice Pack

≥ 2 years